HDAC2 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human,Mouse,Rat,Monkey
Gen Adı
HDAC2
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | HDAC2 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human,Mouse,Rat,Monkey |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG2b |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | HDAC2 |
| Alternatif İsimler | HDAC2; Histone deacetylase 2; HD2 |
| Gen Kimliği | 3066 |
| SwissProt Kimliği | Q92769 |
| İmmünojen | Purified recombinant human HDAC2 protein fragments expressed in E.coli. |
Uygulama
| Uygulama | WB,ICC |
| Seyreltme Oranı | WB 1:500-1:1000,ICC 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW: 55 kDa; Observed MW: 60 kDa |
Araştırma Alanı
Arka Plan
| In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. |