GSDMD Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Mouse,Rat
Gen Adı
GSDMD
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | GSDMD Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | GSDMD |
| Alternatif İsimler | DF5L; M2-4; Dfna5l; GsdmD-1; Gsdmdc1; 1810036L03Rik |
| Gen Kimliği | 69146 |
| SwissProt Kimliği | Q9D8T2 |
| İmmünojen | Recombinant protein of mouse GSDMD |
Uygulama
| Uygulama | WB,IHC,FC,IP |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:200-1:1000,FC 1:200-1:500,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW:53 kDa; Observed MW:53,31 kDa |
Araştırma Alanı
Arka Plan
| Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D). [provided by Alliance of Genome Resources, Apr 2022] |