GCLM Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
GCLM
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | GCLM Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG,Kappa |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
| Saflaştırma | Protein A |
Antijen Bilgisi
| Gen Adı | GCLM |
| Alternatif İsimler | GCLM;GLCLR;Glutamate--cysteine ligase regulatory subunit;GCS light chain;Gamma-ECS regulatory subunit;Gamma-glutamylcysteine synthetase regulatory subunit;Glutamate--cysteine ligase modifier subunit |
| Gen Kimliği | 2730 |
| SwissProt Kimliği | P48507 |
| İmmünojen | A synthetic peptide of human GCLM |
Uygulama
| Uygulama | WB,IHC,ICC/IF,ELISA,IP |
| Seyreltme Oranı | WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
| Moleküler Ağırlık | Calculated MW:31kD;Observed MW:31kD |
Araştırma Alanı
Arka Plan
| Cell localization:Cytoplasm.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015], |
