CAPON Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human, Mouse, Rat
Gen Adı
NOS1AP
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | CAPON Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human, Mouse, Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% protective protein. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | NOS1AP |
| Alternatif İsimler | CAPON, KIAA0464,NOS1AP,Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein,C-terminal PDZ ligand of neuronal nitric oxide synthase protein, |
| Gen Kimliği | 9722 |
| SwissProt Kimliği | O75052 |
| İmmünojen | A synthetic peptide of human CAPON |
Uygulama
| Uygulama | WB,ICC/IF,FC |
| Seyreltme Oranı | WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100 |
| Moleküler Ağırlık | Calculated MW:56 kDa;Observed MW: 56 kDa |
Araştırma Alanı
| Neuroscience |
Arka Plan
| Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity).In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation (PubMed:33523862). |
