C Reactive Protein (15D4) Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
CRP
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | C Reactive Protein (15D4) Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Saflaştırma | Affinity purification |
Antijen Bilgisi
| Gen Adı | CRP |
| Alternatif İsimler | CRP; Pentraxin 1; PTX1; C reactive protein pentraxin related; |
| Gen Kimliği | 1401 |
| SwissProt Kimliği | P02741 |
| İmmünojen | Recombinant protein of human C Reactive Protein |
Uygulama
| Uygulama | WB,IHC,IF-P |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:200-1:2000,IF-P 1:200-1:2000 |
| Moleküler Ağırlık | 25kDa |
Araştırma Alanı
| Immunology |
Arka Plan
| Serum CRP values are routinely measured to detect or monitor many human diseases and minor elevations of C-reactive protein are predictive of cardiovascular events in patients with coronary heart disease. CRP promotes host defense, is an efficient activator of the classical C cascade, and shown to be opsonic.The opsonic and C activation activities are responsible for the nonspecific host defense activities providing protection in the preimmune stage of acute infections. Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |