BMP4 Mouse Monoclonal Antibody
Konjugasyon: Unconjugated
Mouse monoclonal Antibody
Uygulama
Reaktivite
Human,Rat
Gen Adı
BMP4
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | BMP4 Mouse Monoclonal Antibody |
| Açıklama | Mouse monoclonal Antibody |
| Konak | Mouse |
| Reaktivite | Human,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | Mouse IgG1 |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Purified antibody in PBS with 0.05% sodium azide |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | BMP4 |
| Alternatif İsimler | ZYME; BMP2B; OFC11; BMP2B1; MCOPS6 |
| Gen Kimliği | 652 |
| SwissProt Kimliği | P12644 |
| İmmünojen | Purified recombinant fragment of human BMP4 (AA: 277-408) expressed in E. Coli. |
Uygulama
| Uygulama | WB,ICC,ELISA,FC |
| Seyreltme Oranı | WB 1:500-1:2000,ICC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Moleküler Ağırlık | 46.5kDa |
Araştırma Alanı
| TGF-beta signaling pathway |
Arka Plan
| The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. |
