ApoB (17G7) Rabbit Monoclonal Antibody-EnkiLife

ApoB (17G7) Rabbit Monoclonal Antibody

Summary

Production Name	ApoB (17G7) Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification	Affinity purification

Immunogen

Gene Name	APOB
Alternative Names	ApoB 100; ApoB 48; Apolipoprotein B 100; Apolipoprotein B48; FLDB;
Gene ID	338
SwissProt ID	P04114

Application

Dilution Ratio	WB 1:2000-1:20000
Molecular Weight	516kDa

Background

Functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. Defects in APOB are a cause of familial hypobetalipoproteinemia (FHBL). Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB). Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.

Research Area

Cardiovascular; Lipids / Lipoproteins; Lipid Metabolism; Cholesterol Metabolism; Lipoproteins/Apolipoproteins; Thrombosis; Fibrinolysis; Cancer; Cancer Metabolism; Metabolic signaling pathway; Metabolism of lipids and lipoproteins; Heart disease