68kDa Neurofilament Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human,Mouse,Rat
Gen Adı
68kDa Neurofilament
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | 68kDa Neurofilament Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human,Mouse,Rat |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Saflaştırma | Affinity Purification |
Antijen Bilgisi
| Gen Adı | 68kDa Neurofilament |
| Alternatif İsimler | NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110 |
| Gen Kimliği | 4747,18039,83613 |
| SwissProt Kimliği | P08551,P08551,P19527 |
| İmmünojen | Recombinant protein of mouse 68kDa Neurofilament |
Uygulama
| Uygulama | WB,IHC,ICC/IF,IP |
| Seyreltme Oranı | WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:20-1:50,IP 1:20-1:50 |
| Moleküler Ağırlık | Calculated MW:62 kDa; Observed MW:68 kDa |
Araştırma Alanı
Arka Plan
| Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] |
