53BP2/ASPP2 Rabbit Monoclonal Antibody
Konjugasyon: Unconjugated
Recombinant rabbit monoclonal antibody
Uygulama
Reaktivite
Human
Gen Adı
TP53BP2;ASPP2;BBP
Saklama
Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles.
Özet
| Ürün Adı | 53BP2/ASPP2 Rabbit Monoclonal Antibody |
| Açıklama | Recombinant rabbit monoclonal antibody |
| Konak | Rabbit |
| Reaktivite | Human |
| Konjugasyon | Unconjugated |
| Modifikasyon | Unmodified |
| İzotip | IgG,Kappa |
| Klonalite | Monoclonal |
| Form | Liquid |
| Konsantrasyon | Unconjugated |
| Saklama | Aliquot and store at -20°C (valid for 12 months). Avoid freeze/thaw cycles. |
| Nakliye | Ice bags. |
| Tampon | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein |
| Saflaştırma | Protein A |
Antijen Bilgisi
| Gen Adı | TP53BP2;ASPP2;BBP |
| Alternatif İsimler | TP53BP2;ASPP2;BBP;Apoptosis-stimulating of p53 protein 2 ;Bcl2-binding protein;Bbp;Renal carcinoma antigen NY-REN-51;Tumor suppressor p53-binding protein 2;53BP2;p53-binding protein 2;p53BP2; |
| Gen Kimliği | 7159 |
| SwissProt Kimliği | Q13625 |
| İmmünojen | A synthetic peptide of human 53BP2/ASPP2 |
Uygulama
| Uygulama | WB,IHC,ICC/IF |
| Seyreltme Oranı | WB 1:1000-1:5000,IHC 1:100-1:300,ICC/IF 1:100-1:300 |
| Moleküler Ağırlık | Calculated MW:;Observed MW:124kD |
Araştırma Alanı
Arka Plan
| Cell localization:Cytoplasm, perinuclear region. Nucleus. Note=Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42..This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
